Lipoxygenase pathways in Homo neanderthalensis: functional comparison with Homo sapiens isoforms

ALOX12 (arachidonate 12-lipoxygenase) Homo sapiens

Hugo: ALOX12 Other names: 12-LOX; 12S-type; 12(S)-lipoxygenase; EC 1.13.11.31; LOG12 Location: 17p13.1 Local order: According to NCBI Map Viewer, genes flanking ALOX15 in centromere to telomere direction on 17p13 are: GABARAP 17p13.1 GABA(A) receptorassociated protein, ASGR2 asialoglycoprotein receptor 2, ALOX12 17p13.1 arachidonate 12-lipoxygenase (Homo sapiens), ALOX12P2 17p13 arachidonate 12...

Sexual Dimorphism in the Mandible of Homo Neanderthalensis and Homo Sapiens: Morphological Patterns and Behavioural Implications

Introduction In 1980 the Journal of Human Evolution devoted an issue to papers which examined sexual dimorphism in hominid evolution. Two of the contributing authors, Smith and Trinkaus, independently investigated intersexual differences in skeletal patterning in the middle to late Pleistocene species Homo neanderthalensis. They also sought to link the patterns they identified to aspects of its...

Evidence suggesting that Homo neanderthalensis contributed the H2 MAPT haplotype to Homo sapiens.

The tau (MAPT) locus exists as two distinct clades, H1 and H2. The H1 clade has a normal linkage disequilibrium structure and is the only haplotype found in all populations except those derived from Caucasians. The H2 haplotype is the minor haplotype in Caucasian populations and is not found in other populations. It shows no recombination over a region of 2 Mb with the more common H1 haplotype....

Homo Socialis and Homo Sapiens

The assumption that individuals are behaving rationally can, at times, usefully constrain predictions of individual and collective behavior. However, success in predicting human and group behavior will often require relaxing this assumption of rationality, instead employing evolutionary, neural, and cognitive constraints. One particularly important form of neural and cognitive constraint is tha...

Homo Sapiens